Banca de DEFESA: NATÁLIA GOMES XAVIER

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : NATÁLIA GOMES XAVIER
DATE: 01/02/2022
TIME: 15:00
LOCAL: videoconferencia meet.google
TITLE:

Identification of genomic regionsassociated with the synthesis of bioactive compounds in sorghum to promote human health

KEY WORDS:

Keywords: Sorghum bicolor; Genetical enhancement; Associative Mapping; Molecular Markers; Nutritional and Functional Properties.

PAGES: 93
BIG AREA: Multidisciplinar
AREA: Interdisciplinar
SUMMARY:

In recent years, there has been a growing increase in interest in using sorghum for human consumption, mainly due to the demand for healthier, gluten-free foods with greater nutritional value and a source of bioactive compounds. Bioactive compounds are secondary metabolites that act on living organisms and provide many health benefits, as they have antioxidant, immunomodulatory, anti-osteoporotic, anti-hypertensive, anti-inflammatory, anti-microbial, anti-diabetic and anti-cancer properties, and are considered effective in reducing cardiovascular complications. However, the accessibility, availability and chemical characteristics of bioactive compounds have wide variability between different sorghum genotypes, which results in different behaviors in the food matrix and in the interaction with other food ingredients. As a result, genetic improvement programs have invested efforts in the identification, characterization and quantification of compounds, which is essential for a better understanding of their synthesis pathways and their genetic regulation. In this context, the objectives of the present work were: i) to verify the phenotypic diversity in a panel of sorghum lines evaluated for the composition of bioactive compounds in the grains; ii) to identify, from associative mapping analyzes, genomic regions associated with the concentration of tannins, total phenolics, luteolinidine chloride, apigenenidine chloride and resistant starch in sorghum grains; iii) to develop gene-specific molecular markers for the Tannin 1 gene, which regulates the tannin biosynthesis in sorghum. Thus, the results of the present work can contribute to the discovery of new genes related to the biosynthesis pathway of bioactive compounds in sorghum, in addition to enabling a better understanding of the phenotypic and genetic diversity for bioactive compounds in sorghum. Additionally, the development of a molecular marker for the Tannin 1 gene that can assist the process of genotype selection in Embrapa's sorghum breeding program.

 

 

 

BANKING MEMBERS:
Externo à Instituição - ANTONIO AUGUSTO FRANCO GARCIA
Externa ao Programa - 061.394.806-80 - JANÁINA DE OLIVEIRA MELO - UFMG
Interno - 656.980.886-91 - JURANDIR VIEIRA DE MAGALHÃES - York
Externa à Instituição - KARINE DA COSTA BERNARDINO
Presidente - 303.233.218-44 - MARIA MARTA PASTINA - UNIFESP